Edith Cowan University, School of Medicine, Australia
Title: Appetite control is involved in Immunotherapy with relevance to cardiovascular disease, NAFLD and Diabetes
Dr. Ian Martins is an Editor/Reveiwer for Open Acess Pub/MDPI journals and various other international journals. Appointed as the Chief Editor for International Journal of Diabetes Research (2014-2018), Research and Reviews: Neuroscience (2016-2018) and Journal of Diabetes and Clinical Studies (2017-2018). Conferred with the RICHARD KUHN RESEARCH AWARD-2015 ENDOCRINOLOGY AND METABOLISM. He is a BIT Member (BIT Congress. Inc) with an H-index of 43, (ResearchGate STATs (23), Mendeley STATS (20). He is now a Scientist for The Science Advisory Board (USA) and an Academic with Academia.edu. The total citations over the past 27 years of scientific research has accumulated to approx. 3300. ResearchGate’s analysis available on google, Tweet, Facebook, Lindekin under Ian James Martins’ name places publication Stats RG score higher than 96% of the international SCIENTISTS. Prestigious Recognition of Lifetime Membership by International Agency for Standards and Ratings as Fellow for Diabetes, Medical Science (Nutrition). Winner (World Academic Championship -2017) in Diabetes and Medical Science (Nutrition). Certificates of appreciation from various international conferences have been received in relation to anti-aging, health and disease. Keynote addresses at Innovate Pharma 2017, Innovate Neurology 2017, World Diabetes and Endocrinology Summit-2017 and Pharmacology and Ethnopharmacology 2016.
Appetite control with relevance to immunometabolism has become critical to the treatment of non alcoholic fatty liver disease (NAFLD) and diabetes (1,2). Anti-aging genes (3,4) and their connections to autoimmune disease and mitophagy now identify the anti-aging gene Sirtuin 1 (Sirt 1) to be defective with increased heat shock proteins (HSP) involved in autoimmune disease and mitophagy (5) connected to irreversible programmed cell death in global populations. Appetite control or food restriction is required to maintain the heat shock gene Sirt 1 (6,7) that regulates HSP, amyloid beta and nitric oxide metabolism that are connected to natural killer cell activity, mitophagy and autoimmune disease in diabetes. Nutritional regulation of Sirt 1 with relevance to antimicrobial activity in humans (8) has become important to immunotherapy and the clinical treatment of NAFLD and diabetes. Nutritional diets that contain Sirt 1 activators have become vital to immunotherapy research to maintain immunometabolism and prevent mitophagy. Science and medicine and its relevance to genomic medicine (9) needs to consider Sirt 1 gene expression with its relevance to accelerated immune reactions that trigger acute cardiovascular disease. Various factors need to be considered as the trigger for toxic immune reactions with relevance to the progression of cardiovascular disease, NAFLD and diabetes.